Tri-complex inhibitors of the oncogenic, GTP-bound form of KRASG12C overcome RTK-mediated escape mechanisms and drive tumor regressions in preclinical models of NSCLC

Robert Nichols, Christopher Schulze, Alun Bermingham, Tiffany Choy, James Cregg, Gert Kiss, Abby Marquez, Denise Reyes, Mae Saldajeno-Concar, Caroline Weller, Daniel Whalen, Yu Yang, Zhican Wang, Elena S. Koltun, Mallika Singh, David Wildes, Adrian L. Gill, Richard Hansen, Steve Kelsey, Mark Goldsmith, Jacqueline Smith

 

Sixth AACR-IASLC International Joint Conference: Lung Cancer Translational Science from the Bench to the Clinic; January 11-14, 2020; San Diego, CA.  Poster A06.

 

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