Tri-complex inhibitors of the oncogenic, GTP-bound form of KRASG12C overcome RTK-mediated escape mechanisms and drive tumor regressions in preclinical models of NSCLC

Robert Nichols, Christopher Schulze, Alun Bermingham, Tiffany Choy, James Cregg, Gert Kiss, Abby Marquez, Denise Reyes, Mae Saldajeno-Concar, Caroline Weller, Daniel Whalen, Yu Yang, Zhican Wang, Elena S. Koltun, Mallika Singh, David Wildes, Adrian L. Gill, Richard Hansen, Steve Kelsey, Mark Goldsmith, Jacqueline Smith