Tri-complex inhibitors of the oncogenic, GTP-bound form of KRASG12C overcome RTK-mediated escape mechanisms and drive tumor regressions in vivo

Christopher J. Schulze, Alun Bermingham, Tiffany J. Choy, James J. Cregg, Gert Kiss, Abby Marquez, Denise Reyes, Mae Saldajeno-Concar, Caroline E. Weller, Daniel M. Whalen, Yu C. Yang, Elena S. Koltun, Robert J. Nichols, Mallika Singh, David Wildes, Adrian L. Gill, Richard L. Hansen, Steve Kelsey, Mark A. Goldsmith, Jacqueline A. M. Smith

 

AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA; Poster B077

 

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