RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers

Robert J. Nichols, Franziska Haderk, Carlos Stahlhut, Christopher J. Schulze, Golzar Hemmati, David Wildes, Christos Tzitzilonis, Kasia Mordec, Abby Marquez, Jason Romero, Tientien Hsieh, Aubhishek Zaman, Victor Olivas, Caroline McCoach, Collin M. Blakely, Zhengping Wang, Gert Kiss, Elena S. Koltun, Adrian L. Gill, Mallika Singh, Mark A. Goldsmith, Jacqueline A. M. Smith and Trever G. Bivona

 

Nature Cell Biology Advance Online Publication, 13 Aug 2018

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