Allosteric inhibition of SHP2 suppresses CSF-1R signaling and selectively reduces viability of M2 tumor associated macrophages contributing to anti-tumor immunity

Elsa Quintana, Christopher J. Schulze, Tiffany Choy, Darienne R. Myers, Kasia Mordec, Dylan Daniel, Mark A. Goldsmith, Jacqueline A. M. Smith

 

Proceedings of the American Association for Cancer Research Annual Meeting; 2019 March 29-April 3; Atlanta, Georgia: AACR; 2019. Abstract 5019.

 

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