Discovery of an allosteric inhibitor of SHP2, RMC-4550

Elena S. Koltun, Kevin T. Mellem, Andreas Buckl, Christos Tzitzilonis, Chris M. Semko, Ashutosh S. Jogalekar, Naing N. Aay, Walter S. Won, Tientien Hsieh, Julie Lee, Steven Ballmer, Abby Marquez, Kasia Mordec, Gert Kiss, Jie Jack Li, Nidhi Tibrewal, Frances Zhao, Jeff Jasper, Jacqueline A. M. Smith, Robert J. Nichols, Susan E. Wilson, Mallika Singh, David E. Wildes, Zhengping Wang, and Adrian L. Gill

 

Proceedings of the American Association for Cancer Research Annual Meeting; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; 2018. Abstract 4878.

 

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