Research: Senior Research Associate, Medicinal Chemistry

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit elusive frontier targets within notorious growth and survival pathways, with particular emphasis on RAS and mTOR signaling pathways. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.


As a key member of the Chemistry team, you will be part of an integrated, multidisciplinary research team making significant contributions toward the discovery of important new drug candidates. Your responsibilities will include:

  • Synthesizing biologically active compounds, including the design and execution of the synthetic routes, purification of final targets, and participating in analog design.

  • Plan and execute assigned experiments to support research activities and project goals.

  • Recommend alternatives, research new methods and techniques, and proactively seek out others to identify solutions to challenges.

  • Present research findings to Medicinal Chemistry team and management.

  • Partner in the scientific activities of other outstanding medical chemists, including Ph.D. scientists and create an environment where all ideas are heard.

Required Skills
  • B.S. or M.S. degree in organic chemistry with strong understanding of medicinal, organic, and synthetic chemistry.

  • Over 5 years of drug discovery experience in preclinical medicinal chemistry research in biotech and/or pharma companies.

  • Familiar with modern synthetic, organic chemistry techniques and instrumentation.

  • Well versed in synthetic methodologies and can independently design and execute synthetic procedures.

  • Strong written and verbal communication skills to work with interdepartmental teams.

  • Ability to multi-task, be efficient and well-organized, and work collaboratively as a team-player with high energy for our small company environment.

  • Innovative team-player with high energy for our fast-paced environment