Research: Scientist I/II, Cancer Immunology

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit elusive frontier targets within notorious growth and survival pathways, with particular emphasis on RAS and mTOR signaling pathways. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.


As a key player in our cancer immunology team, you will:

  • Integrate a deep knowledge of tumor immunology and immunotherapy to maximize the development of novel targeted therapies.

  • Use immunology techniques to perform cutting-edge studies, in vitro and in vivo, to interrogate key scientific questions about established or candidate drug targets and therapeutic mechanisms.

  • Lab-based role: Independently design and execute experimental strategies, using cellular and molecular immunological techniques, to investigate target biology and therapeutic mechanisms of action in in vivo immuno-oncology models.

  • Collaborate with biochemists, cell biologists and pharmacologists to generate novel insights that fuel drug development as a member of a cross-functional project team.

  • Manage and analyze experimental data and present experimental results at internal meetings and scientific conferences.

  • Establish collaborations with leading academic research groups in the tumor immunology field.

  • Represent REVOLUTION Medicines with external organizations.

Required Skills
  • Ph.D. degree in immunology, cancer biology or a related discipline with demonstrable track record of excellence in tumor immunology and/or immunotherapy (Sci. I). Post-doctoral, or relevant industry experience, will be considered (Sci. II) but not necessary.

  • Strong track record of research productivity as evidenced by high-quality, impactful publications.

  • Understanding of intracellular cell signaling in immune cells and cancer cells is required.

  • Previous experience with in vivo tumor growth assays is desired. Knowledge of models that interrogate and modulate cells and mediators of the innate and adaptive immune system would be an advantage.

  • Extensive hands on experience in ‘state of the art’ immunology techniques including multi-parameter flow cytometric analyses, cytokine analysis, functional assays, imaging, cell biology and molecular biology. Knowledge of manipulation of human PBMCs and functional assays with human immune cells would be an advantage.

  • Rigorous, quantitative and detail-oriented experimentalist with a desire to continue in a laboratory-focused role

  • Excellent written and verbal communication skills.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

  • Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy small company environment.